BIOL2202 Lecture Notes - Lecture 1: Chromosome Segregation, Central Dogma Of Molecular Biology, Developmental Biology
Document Summary
Gene expression dictates cell identity and function. Genes contain both protein coding sequence (exons) and non-coding sequences (introns) In diploid organism, there are 2 copies of every gene. Cell biology: direct observation, labelling cell structures of interest and observing them. Genetics: looking at mutant genes, proteins and the effects on the cell/animal. Genomics and proteomics: looking at all genes or proteins at the same time. Developmental biology: studying differential gene expression and the signals that lead to the mature organism. M chromosome segregation and cell division. G0 temporary or permanent exit from cell cycle. Chromosome the structural unit of genetic material consisting of double stranded dna and proteins. Chromatid one copy of a duplicated chromosome. Sister chromatids identical copies of a chromosome joined by a centromere. Homologous chromosomes chromosome pair that include one from each parent. Goal of mitosis 2 genetically identical daughter cells. Interphase chromosome duplication and cohesion, centrosome duplication.
