BIOM3010 Lecture Notes - Lecture 16: Renal Corpuscle, Renal Function, Renal Cortex
Document Summary
Two kidneys, on the posterior wall of the abdomen, outside peritoneal cavity. Bladder for storage, distensible, up to 700-800ml. Emptying (micturition) voluntary contraction (learned), through urethra. The paired kidneys form a filtrate of the blood that is modified by reabsorption and secretion: urine designated for excretion moves along the ureters to the bladder. Regulation of water and electrolyte volume and osmolarity: sodium chloride, potassium, calcium, phosphate, magnesium. Regulation of acid-base balance: hydrogen ions (ph) Excretion of metabolic waste products and foreign chemicals: nitrogen. Removal of foreign chemicals from blood: drugs, pesticides, food additives. Secretion of hormones: renin controls the formation of angiotensin, erythropoietin stimulated red blood cell production, 1,25-dihydroxy vitamin d3. Distinct zones the cortex, medulla and pelvis. Outer layer is the renal cortex site of glomerular filtration and the convoluted tubules. Inner part is renal medulla location of the longer loops of. Henle, and the drainage of the collecting ducts into the renal pelvis and ureter.
