MEDI2022 Lecture Notes - Delirium Tremens, Substance Intoxication, Alcohol Dependence

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Self-administeration of any substance for non-medical purposes with harmful effects. Substance abuse: alcohol, illicit drugs, prescription drugs, drugs in sport. Some drugs that are abused have a low tendency to causes drug dependence e. g. cannabinoids, lsd. 47% of those with substance abuse have mental health problems. 29% of those with a mental health disorder have a substance use disorder. Substance use disorders: substance abuse, substance dependence. Substance induced disorders: substance intoxication: reversible psychological and behavioural changes due to recent exposure to a psychoactive substance, substance withdrawal: substance-specific syndrome that develops following cessation of or a reduction in dosage of regularly used substances. Dependence ( 3 in 12-month period): maladaptive pattern of substance use leading to clinically significant impairment or distress as manifested by >3 occurring at any time in the same 12 month period. 1 tolerance: need for increased amount to acheive intoxication or diminished effect with same amount of substance.

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