NUTR2101 Lecture Notes - Lecture 13: Clastic Rock, Leaf Vegetable, Folic Acid
Wednesday, 30 May, 2018
NUTR2101 Week 13
Questions note
-Week 7: Glutathione (Glutamate, Glycine and Cysteine) molecule is part of non-
enzymatic system and is an antioxidant Its thiol group in cysteine acts as a reducing
agent to maintain call in reduced state; Glutathione peroxidase is part of the non
enzymatic system. Glutathione is a molecule glutathione peroxidase is an enzyme/ a
functional protein; glutathione peroxidase use glutathione as part of its structure coded
in the DNA with Selenium convert free radicals to non-reactive product e.g. H2O2 to
O2 and H2O
-Nrf2 is a transcription factor bind to DNA promoting the expression of antioxidant
enzyme gene
-transferrin for transport in circulation after hephastin on the basalateral membrane
convert Fe2+ to 3+; hephaestin is not a transporter it is just a converting enzyme;
ceruloplasmin mainly transfer copper and if iron is needed, will convert Fe2+ to 3+ in
circulation
-dry beri beri are more to old adult; wet beri beri is water retention; cerebral beri beri
purely with alcoholism leading fogginess and shakiness
-riboflavin involve in iron absorption so impair loss of iron, anaemia due to less RBCs
type of anaemia
-calcium dominant mineral so calcium-hydroxyapatite but hydroxyapatite means the
same
Nutrition issues in Lifecycle learning outcome
-pregnancy; early stages of life; how we develop preference of eating habits
-ageing; mechanism of ageing hypothesis (ageing process; to understand tooptimise
function and to catch early before developing anti ageing not reversing but see where
intervention can take place); treating ageing and look at symptoms
-lifespan and health span; chronic disease biomarkers of chronic disease and how
nutrition can make difference
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Document Summary
Glutathione is a molecule glutathione peroxidase is an enzyme/ a functional protein; glutathione peroxidase use glutathione as part of its structure coded in the dna with selenium convert free radicals to non-reactive product e. g. h2o2 to. Nrf2 is a transcription factor bind to dna promoting the expression of antioxidant enzyme gene. Dry beri beri are more to old adult; wet beri beri is water retention; cerebral beri beri purely with alcoholism leading fogginess and shakiness. Ribo avin involve in iron absorption so impair loss of iron, anaemia due to less rbcs type of anaemia. Calcium dominant mineral so calcium-hydroxyapatite but hydroxyapatite means the same. Pregnancy; early stages of life; how we develop preference of eating habits. Ageing; mechanism of ageing hypothesis (ageing process; to understand tooptimise function and to catch early before developing anti ageing not reversing but see where intervention can take place); treating ageing and look at symptoms.
