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PHRM4012 (12)

Class Notes for PHRM4012 at University of Queensland

Integrated Patient Centred Care

PHRM4012 Lecture Notes - Lecture 11: Angioedema, Cyp1A2, Loop Diuretic

Heart Failure Left ventricular pulmonary congestion, dyspnoea Right ventricular elevated venous pressure, peripheral oedema, liver congestion Lifestyle: Cease alcohol ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 12: Microbiological Culture, Nonsteroidal Anti-Inflammatory Drug, Quinolone

UTI - do not treat asymptomatic UTI treat symptomatic/pregnant UTI For men 7 days tx Trimethoprim 300mg d for 3 days - (bacteriostatic) inhibit bacterial folate synthesis - precaution: ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 2: Pindolol, Hyperthyroidism, Sleep Apnea

Hypertension - targets (patients with cardio, renal, cholesterol or diabetes problems must treat) o 140/90 o 130/80 for diabetics - lifestyle advice very important o reduc...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 3: Cytochrome P450, Simvastatin, Fluvastatin

Dyslipidaemia - risk of cardiovascular disease increases with raised lipid levels - secondary causes of dyslipidaemia: o alcoholism o diabetes mellitus o hypothyroidism ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 6: Edema, Apple Juice, Biguanide

Diabetes - HBA1c <53mmol/mL, <7% - BSL <10mmol/L (6-10 post-meal) (4-10 resting) - First line: metformin - Second line: GLP1 agonist (exanatide), DPP4i (-gliptin), sulfonylureas, sodium glucose ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 4: Carbamazepine, Orthostatic Hypotension, Diplopia

Bipolar disorder nd - acute manic symptoms 2 gen Antipsychotics + haloperidol o SE ADESHOW anticholinergic (constipation, urinary retention, ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 7: Caffeine, Prochlorperazine, Rivaroxaban

Peptic Ulcer Disease PPI for 7 days Esomeprazole 20mg bd Pantoprazole 40mg bd Omeprazole 20mg bd Rabeprazole 20mg bd +Amoxicillin 1000mg bd for 7 days +clarithromycin 500mg bd for 7 days PPI for 7 days + clarit...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 8: Pamidronic Acid, Diarrhea, Paracetamol

Osteoporosis Calcium supplements: 3 servings of dairy d calcium carbonate 1.5g with food 600mg elemental Ca cheap/ok absorption calcium citrate 2.38g 500mg elemental Ca better absorption in elde...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 9: Diclofenac, Heat Therapy, Flucloxacillin

Osteoarthritis Nonpharmacological: Thermotherapy Massage Physiotherapy Light exercise Paracetamol 1g qid d osteo Panadol 1.33g tds d ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 10: Prokaryotic Small Ribosomal Subunit, Dyscrasia, Bactericide

CAP Mild disease Amoxicillin 1g tds for 5-7 days penicillin Bactericidal; interfere with bacterial cell wall peptidoglycan synthesis by binding to penicillin-binding proteins, eventually leading to cell lysis and dea...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 1: Monoamine Oxidase B, Palpitations, Iron-Deficiency Anemia

Iron deficiency anaemia - serum ferritin iron stores (can be normal even in infection, elderly, hepatic) - elemental iron 100-210mg d - ferrograd 325mg = 105mg - Counselling o Take with fo...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell
PHRM4012 Lecture Notes - Lecture 5: Cefalexin, Clavulanic Acid, Reuptake

Depressive bipolar - Use antidepressant + prophylaxis antipsychotic wean antidepressant off after 1-2 months if possible - Switching from manic/depression SSRI least SSRI inhibits serotonin reuptake ...

Pharmacy
PHRM4012
Associate Professor Neil Cottrell

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