PHRM4012 Lecture Notes - Lecture 9: Diclofenac, Heat Therapy, Flucloxacillin

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Paracetamol: 1g qid d, osteo pa(cid:374)adol (cid:1005). (cid:1007)(cid:1007)g tds d, max 4g d. Steroid injections: rapid relief for 4 weeks, se gi upsets, bleeding, increased infections, diabetes/hyperglycaemia, dyslipidaemia, weight gain, oedema, hypertension, hypokalaemia. Pituitary hypothyroidism (tsh not useful levels: hypothyroidism (acfgil): Car(cid:271)i(cid:373)azole i(cid:374)hi(cid:271)it thyroid hor(cid:373)o(cid:374)e sy(cid:374)thesis: se nausea, vomiting, itching, leucopenia, hepatotoxicity, arthralgia. Propylthioura(cid:272)il i(cid:374)hi(cid:271)its t(cid:1007) to t(cid:1008) (cid:272)o(cid:374)versio(cid:374: se nausea, vomiting, itching, leucopenia, hepatotoxicity, arthralgia. Propanolol 10mg bd: se asthma, diabetes, bradycardia, fatigue, orthostatic hypo. Atenolol 25mg d: se asthma, diabetes, bradycardia, fatigue, orthostatic hypo. Diltiazem 60mg qid: se bradycardia, orthostatic hypo, heart block with bb, constipation. Cellulitis: caused by strep pyogenes strep b/c/g staph aureus, aero fresh(cid:449)ater, (cid:448)i(cid:271)rio salt(cid:449)ater. Cephalexin 500mg qid for 5-10 days: cephalospori(cid:374) (cid:894)(cid:271)a(cid:272)teri(cid:272)idal(cid:895) (cid:271)i(cid:374)d to pe(cid:374)i(cid:272)illi(cid:374)-(cid:271)i(cid:374)di(cid:374)g protei(cid:374)s i(cid:374)hi(cid:271)it bacterial wall synthesis, pre(cid:272)autio(cid:374)s reduce dose crcl <20ml/min, se nausea, vomiting, diarrhoea, rash, blood dyscrasia, counselling, take without regard to food.

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