8392 Lecture Notes - Lecture 7: Hemoglobin, Palpitations, Atmospheric Pressure
20 Jun 2018
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Lecture 7: Altitude 1: Basic Physiology and adaptations
oHaemoglobin conc goes up with higher altitude; because of dehydration
oOxygen availability not as good
oDec air resistance; favors speed and power events
oLong distance; not so good
Slower
Worse for aerobic events; less oxygen available
- Factors affecting HBmass
oCan increase amount of Hb in blood
Carry more oxygen around the body
Good for distance events
oEPO
Produces extra red blood cells
oInc mass of Hb by 6-12% with EPO
Smaller doses over longer time; approx. 11%
oTrain at altitude; inc 4% Hb mass
Improve aerobic capacity and endurance performance
- How high?
oAltitude classification
Near sea level 0-500m SYDNEY
Low altitude 500-2000m CANBERRA
Mod altitude 2000-3000m BOGOTA
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High altitude 3000-5500m LA PAZ, MT BLANC
Extreme altitude more than 5500m EVEREST
- Basic physics
oBarometric pressure decreased with altitude
oPO2 decreases in direct proportion to barometric pressure
- Oxygen availability
oAs PO2 = 0.2093 x barometric pressure
o
Oxygen diffuses from lungs into alveoli than capillaries
Diffusion gradient lessens with higher altitude
Less driving pressure for oxygen to leave lungs and go into blood
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find more resources at oneclass.com
-
o0.3sec blood is saturated with oxygen
Haemoglobin fully loaded with oxygen
oAt attitude
less oxygen around
small gradient
0.8 sec very little oxygen added to blood
Transit time; more like a second for the haemoglobin to be loaded
with oxygen
oEven then; not fully loaded
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Lecture 7: altitude 1: basic physiology and adaptations: haemoglobin conc goes up with higher altitude; because of dehydration, oxygen availability not as good, dec air resistance; favors speed and power events, long distance; not so good. Worse for aerobic events; less oxygen available. Factors affecting hbmass: can increase amount of hb in blood. Produces extra red blood cells: inc mass of hb by 6-12% with epo. 11: train at altitude; inc 4% hb mass. High altitude 3000-5500m la paz, mt blanc. Basic physics: barometric pressure decreased with altitude, po2 decreases in direct proportion to barometric pressure. Oxygen availability: as po2 = 0. 2093 x barometric pressure o. Oxygen diffuses from lungs into alveoli than capillaries. Less driving pressure for oxygen to leave lungs and go into blood: 0. 3sec blood is saturated with oxygen. Haemoglobin fully loaded with oxygen: at attitude less oxygen around small gradient. 0. 8 sec very little oxygen added to blood.
