ANSC3103 Lecture Notes - Lecture 27: Capillary Pressure, Collecting Duct System, Tonicity

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2 types of nephrons: cortical nephrons, also known as superficial nephrons, loops into outer medulla and no association of capillaries. However what the kidney does is reabsorb the water that gives us the ability to create concentration in urine. Generation of medullary hypertonicity: distal convoluted tubules: nacl reabsorption, dilution of the tubules fluid and reabsorption of divalent cations, collecting duct system: final control of the excretion rate of electrolytes, ph and water. Glomerular filtration: filtration through the 3 layers fenestration in the capillaries, acellular basement membrane and slits in podocytes of the glomerulus. What are the different forms of pressure: hydrostatic pressure glomerular capillary blood pressure, plasma colloid osmotic pressure or protein osmotic pressure, hydrostatic pressure in capsule or bowmans capsule hydrostatic pressures. Regulation of gfr: its easily achieved through regulation of capillary pressure via afferent arterioles. And how is the pressure regulated well there is the autoregulation of a single nephron: myogenic reflex and the tubuloglomerular feedback.

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