EXSS2025 Lecture Notes - Lecture 14: Human Musculoskeletal System, Premotor Cortex, Cerebral Circulation

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Lesions across these areas affect movements; want to move but cannot. Pre-frontal = planning of intended future movements or behaviours. Pre-motor = order & sequencing of limb & body movements over time coordinated. Cerebrum (forebrain): pre-frontal, pre-motor & motor cortex area: blood flow activity indicates areas of function of a movement, neural neurons active when we see sensory perception coupled with action. Cerebral blood flow activity (increases) as participants progress from initiating a simple - more complex (sequentially stepped) motor tasks. Evidence of coordination & planning from cortex damage. Animals with premotor cortex damage cannot put motor sequences (co-ordination) together. Lesion of pre-motor cortex = cannot coordinate temporal sequence of bi-manual limb movement. Brinkman (1984: lesion = cannot coordinate temporal sequence of bi-manual limb movement, prevent proper movement functioning, affect premotor cortex. The neural journey motor cortex initiation for motor output:

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