HSBH2008 Lecture Notes - Lecture 10: Lipoprotein Lipase, Lipase, Confounding

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Sitting or (cid:858)sedentary behavio(u)r(cid:859) in title / abstract/ keywords. Time: money, high fitness level, high skills (cid:863) Large amounts of sitting, with some light/mod/vig activity. Physical activity (>1. 5 met or > 3. 5 met or ) Outcome (cv disease, death risk, diabetes, obesity: pa & sb act on our health in different pathways. 2% increase in all-cause mortality risk per hour/day of sitting. All-cause mortality risk apparent increases at >8rs of sitting: risk is flat up to. ~8hours/day, then risk increases above 8 hours (ignore top line: 8 hours is approximately half of waking time, y = risk for premature mortality. Effect of replacing 1 hour of sitting with 1 hour of. 5% (4-6%) risk reduction per hour: substitution effects in terms of premature mortality, dot over 1 = activity is harmful, dot under 1 = activity is beneficial, benefit of swapping sitting with standing, walking &

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