Filter By
Filter Reset
Lectures
  • All Lectures
  • Lecture 1 (2)
  • Lecture 2 (2)
  • Lecture 3 (2)
  • Lecture 4 (2)
  • Lecture 5 (2)
  • Lecture 6 (2)
  • Lecture 7 (2)
  • Lecture 8 (1)
  • Lecture 9 (1)
Top Professors
Semester
Class Notes (1,044,523)
AUS (35,215)
USyd, USYD (4,266)
PHAR (183)
PHAR2823 (16)

Class Notes for PHAR2823 at University of Sydney

Physical Pharmaceutics and Formulation B

PHAR2823 Lecture 3: Solids Advanced 2a
Premium

Solubility isa property Dissolution isa process Solubility isan endpoint representingdissolutioncapacity Size of particleseffectsdissolutionrate Increase SA, increase solubility Dissolution of a solid in a liquid oft...

Pharmacy
PHAR2823
any
PHAR2823 Lecture 1: Solids Advanced 1
Premium

Solids Advanced 1 Different types of solid form 15/8/18 Hydrogenbonding; strongest - Type of strong dipole-dipole bond typicallyhighlypolarcovalent bondsbetween hydrogen and very electronegativeatoms. Dipol...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 2: Bioavailability, Solvation
Premium

Solids Advanced 2 17/8/18 Amorphous drug formulations: High energy and thermodynamically unstable. Need to make sure it doesnt convert back to crystalline in transportation storage. Solubility:low solubility often severe...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 4: Scattering Theory, Contact Angle
Premium

Example ofmilling effects - Processwillinduce disorder onthesurfaceofcrystallatticeand induceamorphous phase - Alteration in surface physical propertiesand stability

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 5: Nanopore, Tunable Resistive Pulse Sensing, Dynamic Light Scattering
Premium

Measurement can be done in Yes,majorityisdone inliquid liquid mostlywant toknowhow particlesreact inliquid big adv ...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 7: Thermogravimetric Analysis, Plasticizer
Premium

a wide range of temperature applicability, excellent quantitative capability. Sharper peak,the moreclean and pureand viceversa. Thermogravimetric analysis Measures changes in massor weight inresponse toincreasesin temperat...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 6: 2.5D, Thermogravimetric Analysis, Calorimetry
Premium

Size of particles made of Yes ,norefractiveindex different materials needed Concentration Yes can calculate concentrationofparticlesin ...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 5: Van Der Waals Force, Opposing Force
Premium

Comparison between glidants and lubricants Flowability: How to measure it: Driving force for a powder toflow? Gravity Opposing force resisting flow? Van der Waals force, electrostatic force, capillary force, frictional for...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 3: Methyl Cellulose, Modified Starch, Silicon Dioxide
Premium

Disintegrating Agents Ensures a tabletbreaks up intosmallfragmentswhen incontact withliquid,allowsfor rapid drug dissolution Basic categories: Starch and itsderivatives(>5)mayaffect compressibilityfor DC Celluloses micro...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 7: Bioavailability, Porosity
Premium

Stage 5: Decompression When the upper punch hasascended,theaxialpressureisrelieved.Theinterparticulatebonds formed must be sufficiently robust towithstandreleaseoftheapplied pressure,allowingaxial elastic recovery totakepl...

Pharmacy
PHAR2823
any
PHAR2823 Lecture 6: Solid-Dosage-Forms6
Premium

Choosing a tabletting process

Pharmacy
PHAR2823
any
PHAR2823 Lecture 4: Solid-Dosage-Forms4
Premium

Water Soluble Lubricants: Hydrophilic Combination of water insolubleand water solublelubricantstoreducethenegative effectsof lubricants PEG isgenerally unreactive and usableforchewabletablets Insufficient lubricants wi...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 1: Friability
Premium

Tablets 31718 Tabletsaresolid preparationscontainingasingledoseofone or more activesubstancesand usually obtained by compressing uniformvolume ofparticles. Advantagesof tablets: Unit dose with accuratedrugdosing The oral...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 8: Viscosity, Talc, Bioavailability
Premium

Coated Tablets 10/8/18 Immediaterelease coatingsdonot affect tabletdisintegration,dissolutionor bioavailability. - Mask bitter tastesand/or odour - Improve product appearance and identity - Enhance ease...

Pharmacy
PHAR2823
any
PHAR2823 Lecture Notes - Lecture 2: Bulk Density, Sorbitol, Calcium Sulfate
Premium

Fillers - Fillers,diluents,bulking agent - Provide a sufficientbulkvolume for compression - Tabletsweighnormallyat least 50mg - Chemically inert - Non-hygroscopic - Compatible - ...

Pharmacy
PHAR2823
any

Log In


OR

Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit