PHAR3818 Lecture Notes - Lecture 16: Vaginal Lubrication, Breast Pain, Hot Flash
Document Summary
Age range: 45-55 (average 51 in australia: natural or induced decline of ovarian function (includes surgical removal of ovaries, decreased circulating levels of oestrogen (90%) and progesterone. 25% suffer severe symptoms, <25% suffer few or no symptoms. Time from onset of menopausal symptoms to the last menstrual period. Symptoms start during peri-menopause which occurs approximately 4 years before menopause and lessen with time. Anxiety, mood swings, depression, memory loss, lack of concentration. Change in sexual function, palpitations, aches and pains, urinary problems, sleeping difficulties, tiredness. Progestogen deficiency symptoms: overheating, hot flushing, night sweats. Effects on libido, memory, and energy levels may be due to oestrogen, progestogen or testosterone changes. Long-term risks: decrease in bone density that may lead to osteoporosis - average 10% loss of bone mass in. Increased cholesterol and lipid levels: ongoing problems with memory. Reduce morbidity and mortality associated with deficiency of sex steroids: minimize risks associated with any therapies.