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Class Notes for PHAR3819 at University of Sydney

Gastrointestinal

PHAR3819 Lecture Notes - Lecture 6: Irritable Bowel Syndrome, Inflammatory Bowel Disease, Visceral Pain
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PHAR 3819 Gastrointestinal Stefani Anastasieska Irritable Bowel Syndrome (IBS) Inflammatory Bowel Disease (IBD) Irritable Bowel Syndrome Symptoms Abdominal pain, bloating and spasm Diarrhoea (Fast gut) Constipation (Slow...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 4: Indigestion, Peptic Ulcer, Esophagogastroduodenoscopy
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PHAR 3819 Gastrointestinal Stefani Anastasieska Complementary Medicine in Gastrointestinal Disorders Functional Dyspepsia and Irritable Bowel Syndrome Functional dyspepsia Functional gastroduodenal disorder Has a prevalen...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 9: Nk1 Receptor Antagonist, Chemoreceptor Trigger Zone, 5-Ht3 Receptor
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PHAR 3819 Gastrointestinal Stefani Anastasieska Gut Drugs Nausea and Vomiting Regulated by an area in the brain stem (called the vomiting centre) which receives input from the chemoreceptor trigger zone in medulla (i.e. t...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 5: Diabetes Mellitus Type 2, Natural Killer Cell, Rheumatoid Arthritis
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PHAR 3819 Gastrointestinal Stefani Anastasieska Immunology Inflammation Inflammation involves a continual ubiquitous cascade of complex signaling pathways and processes t at are initiated and maintained by the immune syst...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 2: Imidazole, Side Chain, Histamine
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PHAR 3819 Gastrointestinal Stefani Anastasieska H 2ntihistamines Histamine N(pi) = closest to side chain, N(tele) = further away Ethyl amine side chain Imidazole ring 5 membered ring Tautomerism Red box Predominant form(...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 3: Proton-Pump Inhibitor, Thioamide, Benzimidazole
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PHAR 3819 Gastrointestinal Stefani Anastasieska Proton Pump Inhibitors The Proton Pump H+, K+ATPase located in parietal cell s Responsible for transferring gastric acid from canaliculus to the stomach lumen Secretes acid ...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 13: Varicella Zoster Virus, Hepatitis A Vaccine, Hepatitis B Vaccine
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PHAR 3819 Gastrointestinal Stefani Anastasieska Hepatic Disease 2: Viral Hepatitis and Fatty Liver Disease Acute Viral Hepatitis Most common cause of hepatitis and jaundice Hepatitis A Hepatitis B Hepatitis C Unspecified ...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 11: Carbohydrate Metabolism, Lipid Metabolism, Bilirubin
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PHAR 3819 Gastrointestinal Stefani Anastasieska Hepatic Function and Dysfunction Case History A 43yearold man is admitted to hospital suffering from occasional vomiting, jaundice and hallucinations. Laboratory tests: elev...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 12: Viral Hepatitis, Alkaline Phosphatase, Liver Biopsy
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PHAR 3819 Gastrointestinal Stefani Anastasieska Hepatic Disease 1: Drug Induced Liver Injury Monitoring and Diagnosing Liver Disease Establishing a Cause Possible causes: o Poisons o Infections o Diet and lifestyle o Mali...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 14: Alcoholic Liver Disease, Glycogen Storage Disease, Hepatic Encephalopathy
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PHAR 3819 Gastrointestinal Stefani Anastasieska Hepatic Disease 3: Hepatic Cirrhosis Cirrhosis is scarring of the liver that involves the formation of fibrous (scar) tissue associated with the destruction of e t normal ar...

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PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 1: Peptic Ulcer, Indigestion, Helicobacter Pylori
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PHAR 3819 Gastrointestinal Stefani Anastasieska Dyspepsia Dyspepsia is an umbrella term, which encompasses all the upper GI problems, such as GORD, peptic ulcer disease and functional dyspepsia. Acid Suppression Antacids ...

Pharmacy
PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 7: Ulcerative Colitis, Immunosuppressive Drug, Azathioprine
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PHAR 3819 Gastrointestinal Stefani Anastasieska Pharmacogenomics and IBD IBD Two related but different diseases: Ulcerative colitis Chronic inflammation of GI Crohns disease Dysregulation of the mucosal immune response Me...

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PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 10: Reactive Oxygen Species, Viral Hepatitis, Bilirubin
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PHAR 3819 Gastrointestinal Stefani Anastasieska Liver Toxicity Toxic liver injuries can be a serious problem, and can arise from acute or chronic exposure of chemicals or drugs. This toxicity usually coincides with metabo...

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PHAR3819
Philip Kwok
PHAR3819 Lecture Notes - Lecture 8: Inflammatory Bowel Disease, Naproxen, Isotretinoin
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PHAR 3819 Gastrointestinal Stefani Anastasieska Complementary Medicines: IBD The inflammatory bowel diseases (IBDs), consisting of ulcerative colitis (UC) and Crohns disease (CD), are characterized by chronic inflammation...

Pharmacy
PHAR3819
Philip Kwok

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