PHAR4823 Lecture Notes - Lecture 14: Pharmacoepidemiology, Clinical Pharmacology, Biostatistics
23 Jul 2018
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Document Summary
Pharmacoepidemiology is the study of the use and effects/side-effects of drugs in large numbers of people with the purpose of supporting the rational and cost-effective use of drugs in the population thereby improving health outcomes. Especially important for safety assessments: when a medicine first comes to market there is limited evidence of its health effects. Infrequent and longer-term harmful effects often discovered only in the post-market period. Estimated 230,000 hospitalizations per year in australia, cost of . 2 billion. A need to understand and assess pharmacoepidemiological research for: The aim of pharmacoepidemiology is to examine real world" experiences and it relied primarily on observational research, which is mainly post-market studies. The limits to pre-market rct evidence are that it is too short-term, too few people exposed and often, vulnerable patients are excluded. Two main types of observational studies of medicine use. Treated and untreated similar except for treatment assignment.
