CAM202 Lecture Notes - Lecture 7: Folate Deficiency, Oral Mucosa, Tooth Pathology
Document Summary
Learning objectives: understand the aetiology, pathogenesis, macroscopic and microscopic features and clinical presentations of. Leukoplakia - the problem of the "white patch" in the mouth: dental pathology - cysts and tumours, tumours of oral mucosa. Salivary gland pathology including: infection, inflammation and tumours. Glossitis: beefy red tongue secondary to atrophy of the papilla, thinning of mucosa, b12, b2, b3, b6 vitamin deficiency, iron, folate deficiency, consider: irritants (food/medication/alcohol, dry mouth (sjogrens) Infections (90%) most commonly hsv infections and mycoplasma pneumoniae, but also. Varicella, adenovirus, cmv: medications (<10%), anti-inflammatory, antibiotics, anticonvulsants, collagen vascular diseases, may be idiopathic. Stevens johnson syndrome: wide spread mucosal and skin ulceration which can be severe and life threatening rare complication of medication use, most commonly antibiotics/fungals/virals, anticonvulsants, anti-inflammatories. Variant: toxic epidermal necrolysis: diffuse necrosis and sloughing of epithelium (>30% bsa) - looks like extensive burns. Oral mucosal "white patch: oral candidiasis (thrush) Immune system, oral flora: oral mucosal involvement in systemic disease, hairy leukoplakia (hiv)
