300816 Lecture Notes - Lecture 1: Myasthenia Gravis, Cytopathology, Autoimmune Disease
Document Summary
Constitutes a large body of scientific knowledge and investigative methods essential for understanding disease. Autopsies; internal examination of bodies after death clarifies the nature of diseases. Microscopy to study diseased tissues has allowed changes to be detected, increasing our understanding of diseases. This impact is exemplified through advances in our knowledge of the biochemical basis of congenital disorders and cancers. Clinical medicine is based on a longitudinal approach to a patient"s illness (history, examination, diagnosis and treatment). Haematology is study of disorders of cellular components of the blood. Toxicology is the study of effects of poisons. Cytopathology is investigating disease through isolated cells. Observation of the effects of manipulations on experimental systems, such as animal models of disease or cell cultures. Histochemistry is the study of chemistry of tissues, after treated with specific reagents. Immunohistology and immunofluorescence employ antibodies to visualise substances in tissue sections. Involvement of cellular and extracellular components in disease. Nucleus; genetic disease such as huntington"s disease.
