Dna microarray is a collection of spots attached to a solid support such as a microscope slide each spot contains one or more single-stranded. Arrays make it possible to put down large quantities of very small (100 micrometre diameter) spots on a single slide. Dna fragment molecule that is complementary to a single dna sequence. A variation of this technique allows the gene expression of an organism at a particular stage in development to be quali ed (expression pro lling). Rna in a tissue is isolated and converted to labeled cdna. This cdna is then hybridized to the fragments on the array and visualization of the hybridization can be done. Since multiple arrays can be made with exactly the same position of fragments they are particularly useful for comparing the gene expression of two different tissues, such as a healthy and cancerous tissue.