IMED1002 Lecture Notes - Lecture 5: 5.8S Ribosomal Rna, Nucleic Acid Double Helix, Untranslated Region
15 Aug 2018
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Lecture #11: chromosomes: dna packaging: 26th march 2018: Be able to define: chromatin, nucleosome, diploid, haploid, polyploid, cytogenetics, somatic, germ line, karyogram/karyotype. Be able to describe the levels of dna organisation. Understand that chromosomal dna is packaged and coiled. Describe the three elements required for chromosomes to be copied. Understand the process of chromosome banding (main features) Be able to describe how chromosomes are prepared for cytogenetic analysis. Chromosome: structure that consists of a single molecule of dna (2. Dna is packaged with protein- combination of dna and protein= chromatin. During cell division (m phase) chromatin is highly condensed- into chromosomes. Only in a very small window of the cell cycle do we see chromosomes in this highly compacted structure. Sister chromatid= 2 copies of a chromosome held together at the centromere. Chromosomes have 2 fundamental roles: faithful transmission and appropriate expression of genetic information. A diploid organism has 2 sets of chromosomes organised as.
