IMED1004 Lecture Notes - Lecture 94: Milk Allergy, Mast Cell, Allergic Response

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Allergic immune response is an inappropriate immune reaction towards molecules in the environment (air/food) that are not dangerous for us. Either they spontaneously disappear (egg allergy, cow milk allergy) or they persist for the whole life (food allergy to peanuts--anaphylaxis, hay fever) Start with eczema- then to asthma and then hay fever atopic match (progress onto one allergic to another_ Having one allergic disease in early life can lead to having other manifestation of allergy later on (atopic march) What can be done to prevent allergy? need to know what are the mechanisms underlying allergic disease development need to identify factors are protective or that increase susceptibility. Allergic diseases are due to: effector immune response towards a non-dangerous antigen in the environment start attacking something that is not dangerous at all not allergic when you mount a regulatory immune response. An optimal immune system requires balanced and adapted effector and regulatory immune responses:

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