BIOL 3523 Lecture Notes - Lecture 6: Beta-Lactamase, Beta-Lactam, Zoonosis
Document Summary
Single-stranded rna paramyxovirus causes generation of syncytia causes cells die, slough off and plug the airways. No effective antiviral medications and no vaccine available. Can give passive immunity (immunoglobulins) to those babies who are born premature or in the winter months. Transmitted from urine and feces of infected rodents to humans (zoonotic disease). Causes shock an death in 30% of patients because the inflammatory response to viral antigen causes capillaries to leak plasma into lungs, suffocating the patient and causing blood pressure to fall. No proven treatment and disease is highly fatal. Fungal infections are not common in healthy individuals and would suggest that you are immunocompromised if you became infected with a fungus. You get valley fever from dust and soil. If you have this it would suggest an underlying. Azoles target ergosterol pathway so it disrupts the cell membrane. The can be pimples when they are smaller, if adjacent tissues are infected it"s a immunodeficiency.
