LATI 3503 Lecture Notes - Lecture 1: Rhinovirus, Carcinoma, Fibroblast
Document Summary
Many of viruses can be grown in cell cultures or in fertile eggs under strictly controlled conditions. Growth of virus in animals is still used for the primary isolation of certain viruses and for studies of the pathogenesis of viral diseases and of vial oncogenesis. The primary purpose of virus cultivation is: to isolate and identify viruses in clinical samples, to do research on viral structure, replication, genetics and effects on host cell, to prepare viruses for vaccine production. The animals are observed for symptoms of disease and death: then the virus is isolated and purified from the tissue of these animals, live inoculation was first used on human volunteers for the study of yellow fever virus. Inoculation is mainly done for production of vaccine of influenza virus, yellow fever, rabies: most of avian viruses can be isolated using this method, amniotic sac: