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Lecture 6

BISC 102 Lecture Notes - Lecture 6: Phosphocreatine, Creatine Kinase, Phosphagen

8 pages50 viewsFall 2015

Department
Biological Sciences
Course Code
BISC 102
Professor
Tony Leyland
Lecture
6

This preview shows pages 1-2. to view the full 8 pages of the document.

Energy
-
-  !" !"!# "$#$#!
Power
-" %"!#!#&% '
Power Output
-!# ! !
-"!#  "! !#
-
$#$()%*!+!,!-
Capacity
- ""!%" "! 
Adenosine triphosphate (ATP) – "!# !" !
-%%"!!.%!"%#%*!#"
-
!
.!""!! !" ! !!
2 Metabolic processes for producing ATP:
Anaerobic Processes
-!/!0#!
Aerobic Processes
-0#!1% 
3 Energy Systems – !1!!!#!#" 1
&Phoshagen2,0"%"!Anaerobic2+0"Aerobic'
1) Phosphagen System – "!#3""  !#
 "!%%"&4'
-!" "* 
--ATPase-"!!%%"&'5!#"! %%"&'5!#
--Creatine Kinase-55!#
-61"enzymes * ""7" % "" !
- Couple Reaction – !#"! % "" !1"!%
% "" !
-3"0$8) 
-9#%"-"!# 
-"!! :
- FASTEST ATP – Predominates in high-power, short-duration activities –
!!#.;!#.%!#
2) Glycolytic System – <"  " !#
-!" 3# "
- Glucose *#"%" 
- Anaerobic Glycolysis (Glycolytic System)*  "!#!#"
- Glycogen 3%"!#"4!1"! ! -=
- Glycolysis – % ""!# #!4# 
8 # -,
- "!1">  
- Produce ATP rapidly during severe exercise when O2 demand > O2 supply
– for approx. 60-90 sec.
- Local muscle fatigue - " ! " "" "" "!
!" 1"!7"!!  !" !  ""#
-RELATIVELY FAST ATP not as good as Phosphagen sys.
- Resynthesize more ATP than Phoshagen sys.
- Limited ATP
- Predominately for the “kick” at the end of the race
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3) Oxidative System – " 
-%!!#%,!" 
- For daily situations; Predominate in Low-intensity, Longer duration (>2/3
min)
- Sarcolemma – "!  
- Sarcoplasm –#"!*"! !!$?:@%!7
#  "
- Mitochondria – !7"  ! "
* " @% 
  "%".".!
Aerobic Carbohydrate Breakdown (Aerobic Glycolysis) < 1g carbohydrate = 4kcal of
ENG>
Glycogen glucose  pyruvate  Acetyl – CoA  Kreb’s cycle  e- transport chain + O2  CO2 +
H2O + ATP
= A
1) Glycolysis
-B%,.1"-acetyl –coenzyme A &" *'@!" "
2) Kreb’s Cycle – Citric Acid Cycle
-C % "" !%, @9!*1
"&0"!'
3) Electron Transport Chain (ETC)
-%# #!.=D  "!#!"
-%# .=E 
KEY:
-"%""!F!*" ""!%#!!A!!
% ! !$
-   &=G*+)'%"!!"  &,*='
-?H ! """!!
Oxidation of Fat Breakdown (Aerobic Lipolysis) < 1g fat = 9kcal of ENG>
Fat  fatty acids  beta oxidation  Acetyl-CoA  Krebs cycle  e- transport chain + O2  CO2 +
H2O + ATP
-#" "1"" "%
-"!@I).)))*I(.))) "18()) "! .+))!1.E)!
-" "
- Carbohydrate H !%"!"! 0#!
!3!#%#%*!!0 
-# %! %central nervous system (CNS) !!!*
"1"! !!
Protein Metabolism < 1g protein = 4kcal of ENG>
Protein  amino acids  deamination  Krebs cycle  e- transport chain + O2  CO2 + H2O + ATP + urea +
ammonia
- Amino acids – !# "."!7 $
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-" !#!#"!0 &2D)!'3$#$""%!!#3 "
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- Deamination – !#!!"!" J
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