BCHM 3P01 Lecture Notes - Citric Acid Cycle, Acetyl-Coa, Cellular Respiration

96 views12 pages

fuchsiaweasel270

20 May 2014

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

In the presence of oxygen, pyruvate is completely oxidized to carbon dioxide and. The complete oxidation of pyruvate in the presence of oxygen is known as cellular respiration. Respiration as a whole involves 3 sets of enzymes in independent but highly interwoven metabolic pathways. The main portion of carbohydrate, fatty acid and amino acid oxidation occurs in the mitochondria via the cac. Also known as the tricarboxylic acid (tca) cycle or the krebs cycle. In addition to fuel oxidation a critical feature of the cac is that it also generates biosynthetic precursors to be used in a variety of pathways : glucose synthesis gluconeogenesis. Precursor: acetyl coa (via citrate: amino acid biosynthesis. Pyruvate needs to cross the imm via a carrier protein that facilitates the cotransport of protons. Need the proton gradient in order to bring pyruvate into the mitochondria. Pumping of pyruvate is performed by pyruvate transfer protein (ptp) at cost of proton motive force.

Related Questions

force times distance

Question 48

Soccer (assuming field player) is a sport which is 90% aerobic.

True

False

Question 50

Glucose is necessary for fatty acid oxidation because...

		its derivative, pyruvate, is condensated with carbonic acid to form oxaloacetate, which in turn is a necessary carbon compound in the citric acid cycle
		it is needed to convert fatty acids to fatty acyl-CoA which in turn is oxidized to acetyl CoA
		glucose is decarboxylated into cytochrome oxidase which is a necessary intermediate in the citric acid cycle
		its derivative, acetyl CoA, is condensated with carbonic acid to form lactase, which in turn is a necessary carbon compound in the citric acid cycle

Question 51

In aerobic ATP production, the role of oxygen is to...

		to keep the electron transport chain operational
		to accept electrons from the 3rd cytochrome and thereby oxidizing it so it can accept new electrons
		act as a oxidizing agent by accepting electrons from the electron transport chain and combining with hydrogen ions (protons)
		all of the above

Question 52

The primary purpose of the citric acid cycle is...

aerobic glycolysis

gluconeogenesis using lactate

the decarboxylation of carbon compounds to produce NADH.

the shuttling of hydrogen ions through the inner mitochondrial membrane

Question 55

Which of the following is the best predictor of marathon running performance?

	A.	Maximal rate of pyruvate oxidation
	B.	Maximal rate of lactate formation
	C.	Amount of adipose tissue triglycerides
	D.	Pre-race blood glucose concentration

emeraldfly517

Which of the following is common to both aerobic and anaerobicmicrobes?

	Fermentation
	An electron transport chain
	Pyruvate oxidation
	Glycolysis
	All of the above

The primary purpose of catabolism is

	generation of ADP.
	generation of ATP.
	oxidation of NADH to NAD⁺.
	degradation of organic molecules.
	biosynthesis.

What is a fate of pyruvate during alcoholic fermentation byyeast?

	It is reduced to lactic acid.
	It is oxidized to form glucose and carbon dioxide
	It is cleaved to form acetylaldehyde and carbon dioxide.
	It is catabolized in glycolysis.
	It is oxidized to form lactic acid and carbon dioxide.

Electrons needed to reduce an oxidized electron acceptor areprovided by

	a) externally provided compounds such asH<sub>2</sub>, lactate or formate.
	b) an intermediate electron carrier such as NADH.
	c) 0<sub>2</sub>.
	d) Both a and b
	e) All of the above

How are aerobic respiration and anaerobic respirationsimilar?

	Both use oxygen as a terminal electron carrier.
	These are other names for glycolysis.
	Both utilize inorganic molecules as terminal electronacceptors.
	Neither receives electrons from glycolysis.
	Anaerobic respiration does not exist in microbes.

The conversion of phosphoenolpyruvic acid (PEP) topyruvate

	a) releases CO<sub>2</sub>.
	b) involves the conversion of ADP and ATP.
	c) involves substrate-level phosphorylation.
	d) Both a and b
	e) Both b and c

Which of the following is the best definition offermentation?

	The reduction of glucose to pyruvic acid
	The complete catabolism of glucose to CO₂ andH₂O
	The oxidation of a carbohydrate with organic molecules servingas electron donors and acceptors
	The production of ATP from glucose
	The production of ethanol from glucose

A reaction that yields energy has a

	positive ?G_o?.
	negative ?G_o?.
	positive ?E_o?.
	negative ?E_o?.
	negative ?H_o?.

Oxidation and reduction reactions are always coupledbecause

	a) electrons generally accompany protons.
	b) protons generally accompany protons.
	c) electrons cannot exist free in solution.
	d) Both a and b
	e) All of the above

10.

Which of the following is true of aerobic respiration?

	It involves the reduction of oxygen.
	It involves the oxidation of oxygen.
	It involves the reduction of lactic acid.
	It involves the oxidation of lactic acid.
	It does not generate ATP.

plumgnu195

1) The complete catabolism of glucose results in the generation of ___________ ATP.

	1.	29
	2.	100
	3.	20
	4.	50

2) The presence of _____________________ is a determinant factor on whether pyruvate continues its metabolism into the Krebs cycle.

3) As humans we breath in air that contains oxygen and breath out carbon dioxide . The oxygen we consume it is used in the metabolism of glucose in the ________________________.

electron transport chain as an acceptor of electrons

anaerobic respiration

citric acid cycle

4.conversion of pyruvate to acetyl-CoA

4) A glucose molecule can generate energy, but only if sufficient amount of energy is invested to initiate the chemical reactions that are involved in the catabolism of the glucose molecule.

True

False

5) The ___________________ of glycogen from individual/separate molecults of glucose is an ___________________ reaction.

	1.	breakdown, endergonic
	2.	breakdown, exergonic
	3.	synthesis, endergonic
	4.	synthesis, exergonic

BCHM 3P01 Lecture Notes - Citric Acid Cycle, Acetyl-Coa, Cellular Respiration

Document Summary

Get access

Related Documents

MCDB 310 Lecture Notes - Lecture 15: Citric Acid Cycle, Pyruvate Dehydrogenase Complex, Acetyl-Coa

BSC 310 Lecture Notes - Lecture 18: Oxaloacetic Acid, Flavoprotein, Cytochrome

BSC 310 Lecture Notes - Lecture 12: Pentose, Glycogen, Anabolism

Related Questions