BIOL 1F25 Lecture Notes - Lecture 11: Protein Phosphatase 1, Memory Consolidation, Reward System
11 Jun 2015
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Problems with involvement of synaptic changes in ltm formations: different areas of brain involved in formations vs storage (studies of h. m, memory reactivation might lead to further changes in those synapses, which might. February 25, 2015. eventually lead to memory erosion. Theory: factual memories initially dependent on hippocampus, are eventually consolidated in the neocortex. Then reactivation of memories is not purely reactivating the same neutrons and synapses that were involved in the initial acquisition of memory! Memories are persistently stores in individual neurons through modi cations of dna. Suggests it unlikely that stable memories can be explained by the unstable phenomenon of synaptic changes. *ltp is the prevalent cellular theory of learning and memory. How do memories get from short-term to long-term: not merely time, build meaningful links, repetition. Enhancement and impairment of consolidation: evaluation of importance. Evaluation of something as exciting or important can enhance it"s consolidation. Exciting experience activates sympathetic system ( ght/ ight); gets release of adrenaline.
