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Lecture 12

BIOL 1F25 Lecture Notes - Lecture 12: Lysine, Cocaethylene, Vasoconstriction

Biological Sciences
Course Code
Gaynor E Spencer

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BIO1F25 LEC12 March 2, 2015.
-derived from the coca bush
-CNS stimulant, regulated as a narcotic
—stimulates release of brain chemicals that play a role in mental alertness and excitation
-exhilaration and euphoria
-heightened alertness
-greater capability for work
-less fatigue
-less need for food and sleep
Exists in 3 forms:
1. Hydrochloride salt
-white powder
-water soluble
-snorted or injected
street del ears often dilute with similar looking substances (ie cornstarch)
2 freebase forms (ex “crack” cocaine)
-crack/cocaine identified as the greatest drug threat, most contributing to violent and property
crimes in their area
Sigmund Freud:
-cocaine pharmacotherapy:
-used for digestive disorders,
-mental stimulant,
-cure for depression,
-treatment for morphine addiction
Crack Cocaine:
-cocaine powder that is chemically altered into crystals
-warmed to a vapour and inhaled “smoking crack”
—goes directly into bloodstream and brain in concentrated form
-can cause serious medical problems even in first time users
Effects of any drug depend on several factors:
-amount taken at any one time
-user’s past drug experience,
-manner in which drug is taken
-circumstances under which drug is taken
Physiological effects include:
-vasoconstriction (constricts blood vessels)
-increase in blood pressure
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