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Lecture 6

BIOL 1F25 Lecture Notes - Lecture 6: Socioeconomic Status, Web Portal


Department
Biological Sciences
Course Code
BIOL 1F25
Professor
Gaynor E Spencer
Lecture
6

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BIOL 1F25
JAN 8TH 2015
LEC 6
Epidemiology
Incidence & prevalence
Risk factors
Epidemiology= study of factors that inuence frequency &
distribution of a disease
Epidemiology of ALS:
Requires good data on incidence & prevalence over time
oIncidence= # of new cases per year
oPrevalence= # of current cases
ALS is not contagious
ALS is not reportable
Challenging to get comprehensive data
Incidence (# of new cases/ year):
USA: ~2/ 100,000 people
Average age at diagnosis= 55-65 years
~3-4 new cases/ year for people aged >60 years
Canada: ~2/ 100,000 people
Prevalence (# of people living with disease):
USA: ~12,000
~4/ 100,000 people
1.56 times more frequent in men than women
Canada: 2,500- 3,000 currently
Possible risk factors:
Earlier publications had identi$ed several possible risk
factors:
oAge, sex, race
oSmoking
oOccupation
oExposure to heavy metals or other environmental
toxins
Most of theses studies involved relatively small numbers
of subjects (small samples)
Need to study a larger group
Web portal has survey module to assess possible risk
factors
Some examples
oAge
oSex
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