BIOL 2P02 Lecture Notes - Cytosine, Gene Mapping, Thymine

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What we are is described as genes. Genetic variations cause inherited disease: genetic diseases, complex diseases, environmental diseases. In genetic diseases and complex diseases mostly genes but for environmental it is mostly environmental. Locus abstract reference to a gene/maker location on the chromosome. Variable allows people to associate genetic variations with different diseases. Allele a specific variant from of a gene/marker at a particular locus. We are different because we carry different alleles. The reason why females are susceptible for breast cancer is because they have a specific allele that exposes them to breast caner. Single nucleotide differences is what makes us different from each other. Single nucleotide substitution: replacement of one nucleotide with another. Microsatellites or minisatellites: these tandem repeats often present high levels of inter- and intra-specifif polymorphism. Iif repeats are in the gene, too many repeats. Once you get above a certain amount of repeats, you develop a disease.

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