BIOL 2P93 Lecture Notes - Ileocecal Valve, Cholecystokinin, Transport Protein
4 Feb 2013
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Introduction: main fxn of intestinal secretions is to maintain acid/base balance b. Intestines are presented w/ a considerable absorptive load every day: highly efficient absorbs all calories that pass (almost) ii. Glucose & galactose: glut transporter facilitated diffusion transporter; located on apical membrane to transport fructose intracellularly, glut-related carrier present on basolateral membrane & exports glucose to blood *fructose & galactose are converted to glucose in enterocytes* Vi: na/h exchanger & cl/hco3 antiporter => net salt absorption and net hcl, osmotic gradient is created by decreased intraluminal nacl => h2o follows & is secretion reabsorbed. Intestinal fluid secretion: cl-dependent fluid is secreted from villi crypts, provides convective mixing at villus tip & moves crypt substances into lumen by bulk flow. Cholera & rotavirus: cause severe diarrhea that may => dehydration & death if not treated w/ fluids & salts, cures: i, ort (oral replacement therapy) patients drink isotonic solution w/
