BIOL 2P93 Lecture Notes - Meiosis, Reproductive System, Microvillus

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Histology—Male Reproductive System
I. Testes
a. Terms
i. Tunica Vaginalis—caivty surrounding each testis
ii. Pampiniform Plexus—convoluted arteries supplying testes which are
convoluted around the testicular veins => countercurrent temperature
iii. Tunica Albuginia—dense fibrous connective tissue; protective layer
iv. Lobuli testis—each testis is subdivided into ~250 lobules composed of 1-
4 seminiferous tubules
b. Seminiferous tubule
i. basal lamina—ensheaths each seminiferous tubule
ii. peritubular myoid cell—responsible for rhythmic contraction of ST =>
movement of immotile, immature sperm
iii. Sertoli cells—non-dividing tall columnar cells; “nurse” cells; each
surrounds ~50 adjacent spermatogenic cells; sensitive to FSH
1. fxns—coordination of spermatogenesis, production of testicular
fluid, formation of brain-testes barrier
iv. Leydig cells
1. secrete testosterone in response to LH
2. sit in connective tissue between seminiferous tubules
v. Cells
1. Spermatogoinium—proliferate & give rise to new stem cells
2. Spermatocytes—go from 4n 2n (haploid)
3. Spermatids—(1n)
4. Spermatozoa—immature sperm
vi. Spermatogenesis
1. 3 steps—spermatocytogenesis (production of spermatocytes from
undifferentiated diploid precursor cells); meiosis, spermiogenesis
2. Takes 64-74 days for spermatogenesis to take place
3. spermiogenesis—transformation undergone by haploid
spermatids; includes acrosomal formation, nuclear condensation, &
tail formation
a. acrosome—specialized compartment derived from golgi
for egg penetration & fertilization
vii. Cycle of seminiferous tubule
1. Differentiation occurs concurrently across the different levels of
2. there are 6 different stages (groupings)
II. Duct System
a. Rete Testes—series of flattened channels in mediastinum testes
i. lined by simple cuboidal epithelium w/ short microvilli
b. Efferent Ductules—connect rete testes to epididymus
i. lined w/ tall ciliated cells & short non-ciliated cells
c. Epidiymis
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