Class Notes (836,580)
Canada (509,856)
Brock University (12,092)
Biology (1,629)
BIOL 2P94 (40)
Lecture

Lecture 05

1 Page
41 Views
Unlock Document

Department
Biology
Course
BIOL 2P94
Professor
Dirk De Clercq
Semester
Fall

Description
Outline of Lecture 05 (02-19 A; Linden) Membrane Potential 0. Fundamental Concepts + 1) Resting potential is –70 mV, close to E dKe to open K channels 2) Ion distribution gives rise to different equilibrium potentials via Nernst eqn - High Na outside (E = 64 mV) , high K inside (E = -86 mV) 2+ Na - K - Very low Ca inside (E = Ca6 mV), high Cl outside (E = -78 mCl 3) Due to very low capacitance of membrane (5 pF), very few ions most move to achieve equilibrium (Q = CV) 4) Current flow through ion channels can be approximated with Ohm’s Law I. Passive current flow (aka cable property of dendrites and axons) A. Basic observations - At steady state, a point depolarization ΔV is graded: it tails off exponentially according to length scale λ, a measure of the relative resistance of the membrane and axoplasm - Due to resistance (ion channel) and capacitor (neuronal membrane) in parallel, upon current pulse voltage asymptotically increases to steady state value according to time constant τ, the product of resista
More Less

Related notes for BIOL 2P94

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit