BIOL 2P97 Lecture Notes - Lecture 10: Total Pressure, Partial Pressure, Blood Plasma

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Partial pressure is calculated by multiplying total pressure by the percentage. Free vs bound o2 of gas occupied by a specific gas molecule o. For example, o2 provides 21% of all air molecules so po2= 760 mmhg x. 0. 21=0. 21 0. 21 160 mmhg: total pressure (p)= sum of partial pressures (pp) If you were to go to a high altitude where total pressure drops, po2 also drops o. E. g. at 1000, elevation, total pressure=680 mmhg: pressure versus concentration. A: oxygen dissolves, at equilibrium po2 in air and water is equal. Low o2 solubility means concentrations are not equal. Low o2 solubility means: when co2 is at equilibrium at the same partial pressure, more co2 dissolves. Another relevant fact: co2 is much more soluble (20x) in water (and plasma) than is oxygen: gradients and diffusion. The "respiratory membrane" includes the alveolar epithelium and the capillary endothelium.

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