BIOL 2P97 Lecture Notes - Lecture 15: Anaerobic Respiration, Globular Protein, Fraction Of Inspired Oxygen

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Or there is good perfusion with poor ventilation. The amount of fresh air that actually reaches the alveoli per minute. Alveolar ventilation= ventilation rate x (vt dead space volume vd) If they are not matched: -there is good ventilation with poor perfusion(blood flow) Ideally we want v/q to be 1 to 1 but average value across lung is . 80 which tells us we have more perfusion than ventilation. Therefore there is low o2 in the alveolus. Fig c: low o2 in the surrounding tissue is sensed by the arterioles, this causes vasoconstriction called hypoxic (low oxygen state) vasoconstriction, this effectively diverts blood to the well ventilated alveoli. This effectively allows you to redirect blood flow to an area that has good ventilation. This process occurs only in the pulmonary arterioles. In the rest of the body, a state of hypoxia would lead to vasodilation, in an attempt to deliver more oxygen to the tissue.

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