HLSC 1F90 Lecture Notes - Lecture 11: Acute Kidney Injury, Rheumatoid Arthritis, Cerebrovascular Disease

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Clinical finings: examination and family history supported by lab findings. Pathological findings: examination of tissue removed from the body. If not is it the blood chemistry, the distribution of enzymes in the cells. Science of disease diagnosis through examination of organs tissues cells and body fluids. Example: acute renal failure biopsy where collection of lymphocytes are present in the main body of the kidney (interstitium), tubule is blocked, therefore it is an abnormal kidney. 16-year-old stung by a bee presents in er. Signs in hospital respirations: 39 normal: 18, hypotensive blood pressure 69/45 normal: 120, tachycardia (fast heart rate), hives, conjunctival edema (around eye area), swollen lips, drowsy, pale. Acute infection is rare, becomes chronic, cirrhosis can develop, if lasting for 3 decades, there is a risk of carcinoma (cirrhosis liver disease) Diagnostic pathology study of deviation of cell and tissue morphology and biochemistry from normal. How aggressive cells look under the microscope to the pathologist.

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