HLSC 1F90 Lecture Notes - Lecture 22: Lymph Node, Clinical Pathology, Anatomical Pathology

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Pathological indings: examinaion of issues removed from the body. Pathology: science of disease diagnosis through the examinaion of organs, issues, cells, and body luids. Diagnosic pathology: cell and issue morphology and biochemistry. Whether or not the cancer has spread to other parts of the body beyond the primary site. Well difereniated (appear normal, growing slowly, not aggressive) The more immature the cell looks like in the tumor, the higher the grade. General pathology: study of any abnormality manifesing in altered structure and/or funcion of organs, issues and/or cells. Clinical pathology: analysis of body luid and issue samples. Collect a issue sample, imbed it in wax, it it, stain it, and observe it under a microscope. Hyperplasia: increase in cell number (seen in cervical cancer) Metaplasia: reversible change from one mature cell type to another. Dysplasia: change from a mature cell to an abnormal cell. Atrophy: decreased individual cell size or cell number.

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