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Lecture 9

HLSC 1F90 Lecture Notes - Lecture 9: Metaplasia, Histology, Hyperplasia


Department
Health Sciences
Course Code
HLSC 1F90
Professor
Dr.Kelli-an Lawrance
Lecture
9

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HLSC1F90
March17th,2016
PathologyDr.PietrangeliPhD
StrategiesforDiagnosingDisease:
ClinicalFindings:examinationandfamilyhistory
Radiological(imaging)results
PathologicalFindings:examinationoftissueremovedfrombody
Pathology:Scienceofdiseasediagnosisthroughexaminationoforgans,tissues,cellsand
bodyfluids
acutediseasemeansveryseriousandfast
chronicmeansserious,butoveralongperiodoftime
DiagnosticPathologyCellandtissuemorphologyandbiochemistry
Diagnosis=identificationofthedisease
Grade=degreeofdeviationfromnormal
highergradegreaterdeviationfromlookingnormal
Stage=extentofthedisease
didIsticktowhereIamordidIspread?
StagingofCancer
Sizeofthecancer
Invasivevs.noninvasivenatureofthecancer
Lymphnodevsnolymphnodeinvolvement
immunesystemdoesn’trecognizecancerasforeignbecauseit’sfromthebody
lymphnodeholdsontoitcancergrowsinthelymphnode
Whetherornotthecancerhasspreadtootherpartsofthebodybeyondtheprimarysite
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GradingofCancer
TumorGrade
AppearanceofCells
Grade1tumour
Welldifferentiated
(appearnormal,growingslowly,notaggressive)
Grade2tumour
Moderatelydifferentiated
(seminormal,growingmoderatelyfast)
Grade3tumour
Poorlydifferentiated
(abnormal,growingquickly,aggressive)
BranchesofPathology
GeneralPathologystudyofanyabnormalitymanifestinginalteredstructureand/or
functionoforgans,tissuesand/orcells
AnatomicalPathologyanalysisofsurgicalsamples
ClinicalPathologyanalysisofbodyfluidandtissuesamples
DetectingPathologicalChanges
Obviousclinicalchange
Grossorganandtissuemorphology
Histology
Radiologicimaging
Pathologicchanges
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