HLSC 4P99 Lecture Notes - Lecture 4: Perfusion

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Exam: logical cut off point or positivity criteria. If the sweet spot is hit, then you would have a perfect sensitivity. If there was 100% sensitivity and specificity, it would be a gold standard. Pick a spot on the curve that we are happy with. Pick the cut off based on the severity of the disease. It"s important to identify who don"t have the disease (specificity) If your roc lies on the reference line, it"s a coin toss. Exam: if the roc curve is under the line, you calculated it wrong. When it"s a condition that"s in the middle, sensitivity and specificity are both important. The false positive and negative (not their rates). Add these together and compare to the noise of the other one. The one with the least amount of noise is the right one.

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