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HLSC 1F90 (498)


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Health Sciences
Brent Faught

CHSC 1F90 November 13, 2012 Cancer Week #10 Abnormal Cell Growth and Spread - Place or origin is what type of cancer you call it i.e. lung cancer - Cancer is the #1 disease that Canadians die from Probability of Developing/Dying from Cancer - Based on current incident rates (will develop cancer during their lifetime)  40% of Canadian women  45% of Canadian men - Based on current mortality rates (will die from cancer):  24% of Canadian women  29% of Canadian men  (~ 1 in 4 Canadians) - After age of 70 we have less success of helping keep people living without cancer Detecting Cancer - Screening  DRE (easier than biopsy) – middle finger up bum  PSA (easiest than biopsy) - Diagnosing - Prostate cancer: biopsy (sample or slice) - Early detection stops death ** - Cell division: Normal cells take 5-7 days to divide, cancer cells take about 12 hours - Neoplasm turns into Tumor. We can confirm tumor through a Biopsy - Benign (non-cancerous) tumor. Grows through expansion - Malignant (Cancerous) tumor. Grows through infiltration - Cancer spread through circulatory and lymphatic system Cancer “Causing” Theories - Error in cell reproduction (spontaneous errors)  MUTATIONS - External carcinogenic agents  80% of explanation of why people get cancer - Oncogene theory  10% why people get cancer  We all have oncogene but some are not provoked  Oncogene + Carcinogenic Agent = Proto-oncogene Suspected causes of Cancer 1. Occupational/ Environmental Factors CHSC 1F90 November 13, 2012  X-ray  B-rays  Asbestos 2. Social and Psychological Factors  Stress  Depression (decreases immune response) 3. Chemicals in Food  Sodium nitrates: in processed food, the preservatives (once broken down become sodium amines – carcinogenic agent aka really red meat) 4. Biological Factors  Genetic predisposition 5. Medical Factors  DES: (drug that stopped bleeding during pregnancy), girl offspring during that pregnancy were at risk for reproductive cancers 6. Viral Factors  HPV  Hepatitis  Hepatitis B&C Classifications of Cancer - Carcinomas  Epithelial tissue  Most common type of cancer  Spreads through circulatory and lymph systems  Examples: lung cancer, skin cancer, breast cancer, oral cancer  Solid tumor - Sarcomas  Mesodermal tissue  Less common  More aggressive - Lymphomas  Develop and spreads through lymphatic system  Hodgkin lymphoma – Reed-Sternberg cell  Non-Hodgkin lymphoma – 30+ types, more common than Hodgkin’s lymphoma  Solid tumor all over body - Leukemia  Cancer of blood-forming parts of body, including bone marrow and spleen  Abnormal increase in number of WBC’s  Non-solid tumor Sta
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