HLSC 4P95 Lecture Notes - Lecture 5: Transfection, Neurofibromatosis, Polycythemia
Document Summary
You have to write it in your section. Neoplasm- any new tissue formed; always going on. Autonomous- don"t adhere to normal regulatory mechanism (mitosis) Disorganized - the cell structure is not what the origin tissue looks like; general disorganization. Clinical- build a picture on treatments, environment, ect. Experimental- for drugs and research, with in vitro and animal models, rarely humans. Due to the active chromosomes telling the cell to make enough just to survive. Normal (less than normal tissue) vs increased mitosis. Primary tumor- piece of it breaks off and moves to another tissue. Size of the primary [t], lymph node metastases [n], distant metastases [m] I-iv or a-d (us) eg. t1 n0, m0. Though functional and strategic differences exist, there are: Tumors cells produce less or differently and require less to survive due to decrease functions beyond survival. Local, digestive site, metabolic, activation in liver, excreted in urine. Hvp, eptein-barr v (mono), hbv, human t-cell lymphoma/leukemia v-i.