KINE 2P09 Lecture Notes - Lecture 5: Gluconeogenesis, Insulin-Like Growth Factor 1, Hyperglycemia
9 May 2018
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KINE 2P09
Cortisol
- Hydrocortisone
- Increases protein and fat breakdown
- Glucose output from liver
- Decrease inflammation
- Decrease immune system function
- Circadian rhythm
Disorders of the Adrenals
- Cushings syndrome
o Too much cortisol
o Increase glucose in plasma
o Increase liver glucose production
o Decreased immune function
o Fat redistribution
- Addisons disease
o Badly functioning adrenal cortex
o Decreased aldosterone secretion
o Can be fatal
o Decreased cardiac output
o Muscle weakness
o Hypoglycemia
Ovaries
- Estrogens
o Steroid hormone
▪ Regulated by FSH
o Estradiol
▪ Development of sex organs
o Progesterone
▪ Prepares for implantation of fertilized egg
Ovaries and Testes
- Inhibin
o Secreted by ovaries and testes
o Peptide hormone
o Inhibits FSH
Pancreatic Hormones
- Insulin
o IGF-1 production
o Mediator for GH
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