NEUR 2P36 Lecture Notes - Lecture 9: Motion Sickness, Medial Vestibular Nucleus, Brainstem

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The (cid:858)rest(cid:859) of the (cid:272)o(cid:272)hlea (cid:894)the (cid:448)esti(cid:271)ular organ, adja(cid:272)ent to/(cid:271)ehind, the (cid:272)o(cid:272)hlea(cid:895) Responsible for orientation, position (through acceleration rotation force); motion of head through space. Accomplished by shearing force of fluid pushing hair cells at the base of the canals. When the head rotates, the fluid pushes against sets of hair cells; blending them and allowing for depolarization, and releasing glutamate (and other peptides) Difficulties w/ balance (particularly balancing on one food w/ or w/o eyes closed) Dizziness, swirling sensation; sense of distorted motion (acute rotational vertigo) : there may be a vestibular issue (either peripheral or central) Stabilizes the retinal image during rotations of the head. Requires stable eye position in space (as head rotates with a certain speed and direction, so do the eyes in the opposite direction (combination = zero) When the 2 signals are in conflict: Involves disturbance/ injury/ malfunction (ex. infection) to the vestibular apparatus (back portion of the cochlea)

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