KINE 1P90 Lecture Notes - Lecture 12: Cardiac Muscle, Pulmonary Circulation, Mitral Valve
Document Summary
Feedback loops: negaive vs. posiive feedback with examples (temperature regulaion, birth) Filament structure (organizaion of myoibrils, sarcomere, how they"re arranged) Muscle contracion mechanisms (how do ilaments slide on each other bridges, myosin head, acin, binding sites, power stroke etc. ) Bridge vs. stroke bridge is point of connecion of myosin head to acin, stroke is the acion ater that which is pull of the acin towards center of sarcomere by myosin bridge (stroke needs bridge to happen) Sliding ilaments vs. stroke stroke is one acion, sliding is the whole acion involving many strokes unil whole thing is shortened. Decrease in ca2+ turns of sliding process. Thin ilaments on each side of sarcomere slide inward over staionary thick ilaments toward center of a band during contracion. As thin ilaments slide inward, they pull z lines closer together. All sarcomeres throughout muscle iber"s length shorten simultaneously.