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Lecture 2

KINE 2P09 Lecture Notes - Lecture 2: Endoplasmic Reticulum, Oxidative Phosphorylation, Nuclear Pore


Department
Physical Education and Kinesiology
Course Code
KINE 2P09
Professor
Brian Roy
Lecture
2

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Lecture 2, 3
Kine 2P84
Jan 18th 2017
Cell membranes:
“fluid mosaic model”
barrier - semi-permeable
important: !
-containment -energy gradient !
-signal transduction and communication
integral, peripheral, and lipid anchored proteins
Cholesterol assist with the fluidity of the membrane, it will keep it more
fluid if need be or vice versa (balances the consistency, buffer)
Phospholipid (carbohydrates) are for communication and interaction
Cytoskeleton proteins are anchors
Cell Parts:
Nucleus
most cells!
– not red blood cells
stores genetic material !
– Chromatin (DNA) !
– nucleolus (ribosomal RNA or rRNA)
nuclear pores
Mitochondrion
energy production
inner and outer !
membrane
matrix
consumes O2 and makes ATP !
– Krebs/TCA cycle!
– Oxidative phosphorylation
Endoplasmic Reticulum and Ribosomes
network of intracellular membranes
“rough” and “smooth” • Ribosomes !
– protein synthesis
Lysosomes and Peroxisomes
Lysosomes:
– degrading enzymes
– “autophagy”
– Liver - alternate !
bioenergetic function
– White blood cells – bacterial digestion
Critical that lysosomes have a membrane around them because they are very
acidic
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