KINE 2P09 Lecture Notes - Lecture 6: Nuclear Pore, Transfer Rna, Thymine

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Mechanism of protein synthesis: from dna to protein (appendix c) Essential for cell function: muscle contraction contractile protein, enzymes for energy metabolism; synthesis, facilitates reactions, transporters to move molecules in and out (cid:862)pol(cid:455)(cid:373)ers(cid:863) or (cid:272)hai(cid:374)s of differe(cid:374)t a(cid:373)i(cid:374)o a(cid:272)ids. Must be identical for good working order! Dna is a nucleic acid (not a protein) Bases: a(adenine, g (guanine, c (cytosine , t (thymine) Create (cid:1007) letter (cid:862)words(cid:863) to (cid:272)ode for the (cid:1006)0 a(cid:373)i(cid:374)o a(cid:272)ids used i(cid:374) protei(cid:374)s (cid:862)(cid:272)odo(cid:374)s(cid:863) Always guanine to cytosine (g with c) and adenine to thymine (a with t) Need to make copy for protein synthesis in cytoplasm. A (cid:862)(cid:272)op(cid:455)(cid:863) of the (cid:862)(cid:373)essage(cid:863) is (cid:373)ade i(cid:374) rna. Very similar to dna, except u (uracil) replaces t (thymine) Only 1 strand made (copied: pro(cid:272)ess k(cid:374)ow(cid:374) as (cid:862)tra(cid:374)s(cid:272)riptio(cid:374)(cid:863) E. g. , in dna, aaa would become uuu in the mrna. The order of the dna bases dictates the order of the next amino acid in that protein.

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