KINE 2P09 Lecture Notes - Lecture 7: Facilitated Diffusion, Aquaporin 1, Molality

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Lipid solubility of eh molecule: molecules size, the lipid composition of the membrane. Does it happen to any specific extent in humans: vast majority of diffusion in the body is across membranes, most situations in the body we must rely on facilitated diffusin. How much stuff is dissolved in a solution: the total solute concentration of a solution. A double double has more osmolality than a black coffee. Facilitated and diffusion pores (e. g. , aquaporins (aqp1 and 4) Aka (cid:862)water pores(cid:863) (cid:894)protei(cid:374)s(cid:895: pores that lets water molecules move through, some water travels through membranes, aquaporins speed things up, (cid:862)tu(cid:374)(cid:374)els(cid:863, easier for water to pass through hydrophobic regions of membrane. Water diffuse through aquaporins from higher to lower concentrations. Must consider water concentration: always going to go down concentration gradient. High solute concentration (osmolality), then water moves towards it (cid:862) i(cid:373)ple (cid:894)u(cid:374)assisted(cid:895) diffusio(cid:374)(cid:863) a(cid:374)d (cid:862)fa(cid:272)ilitated (cid:894)assisted(cid:895) diffusio(cid:374)(cid:863)

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