SCIE 1P51 Lecture Notes - Lecture 5: Tissue Engineering, Biomaterial, Adult Stem Cell

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Co(cid:374)sidered as (cid:862) pare parts(cid:863) (cid:449)he(cid:374) loosi(cid:374)g the origi(cid:374)al tissue or li(cid:373)(cid:271) We can do this naturally when we scratch or break bones. Some tissues are limited to how much they can regenerate like heart tissue cant regenerate after a serious event like a heart attack. Field of tissue engineering is to find away to regenerate tissues. Made out of wood and had a carved out toe. Used 3d printing to make a functional, customizable limbs. The application of engineering & genetics toward the development of biological substitutes to restore, maintain, or improve functions of human tissue. Must look similar, integrate and function properly with the body. Need to know what proteins need to grow the cells growth factors. Needs to take place in the extracellular matrix (ecm). Need to replicate the conditions for the cells, like bladder cells vs skin cells. Scaffolds need to have them in a structural mass not just a lump of cells.

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