SCIE 1P51 Lecture Notes - Lecture 3: Malaria, Anaphylaxis, Tuberculosis
6 Apr 2016
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Document Summary
Thimerosal: vaccine data safety network, large case-control study of autism and thimerosal exposure currently in data collecting phase. Testing vaccines: safety always monitored once you get past the computer stage, animal model. Phase 1 iv: monitoring for safety and adverse reactions/events. Non human primates (nhp: human testing. Phase 1-iv: monitoring for safety and adverse reactions/ events. Testing vaccines: vaccine licensed for use by government regulators. Health canada and food and drug administration: post license safety surveillance, widespread use often results in previously unseen reactions and more adverse events, these are subject to many studies. Further testing vaccines: monitoring for adverse reactions, monitoring specific populations, canadian adverse events following immunization surveillance system (caefiss) Rare adverse events: meningitis, seizures, stroke, anaphylaxis, allergic reactions, death. Vaccinations: global alliance for vaccines and immunization (gavi, ~1. 5 million children die every year, no effective vaccines for:
