Class Notes (837,434)
Canada (510,272)
Biology (1,140)
BIOL 1010 (90)
Lecture 3

Lecture 3.doc

4 Pages
Unlock Document

BIOL 1010
James Cheetham

DNA, Genes, Chromosomes, Genetics and Heredity Tuesday, September 28, 2010 - last lecture on background material - 30 questions multiple choice, matching questions test - Don’t get scared if you don’t understand things like Cohen paper- posted up for historical value- moving gene from one species to another - If you don’t understand slides, look at book - Don’t memorize parts of cell - We’re concerned with nucleus - Work we do at level of cell o Gene therapy for lymphoma: isolate bone marrow cell, filter out cancerous ones, grow others in petri dish, etc. o Trying to change DNA inside cell - Glossary on WebCT - DNA- hydrogen bonds- strands can be separated by heating them up (lab) - Cell can’t be warmed up- enzymes to unwind DNA- scientists call this the melting of DNA (we call it unwinding) - DNA replication is semi-conservative: one strand of each daughter cell comes from original strand - We use those enzymes as tools to manipulate DNA in the lab, will learn about them - DNA in uncondensed form (chromatin): necessary for replication, because DNA strands have to unwind - Karyotype: picture of chromosomes o Tell gender by last pair of chromosomes - One chromosome comes from each parent- before cell divides, you have homologous pairs - Don’t have to memorize cell cycle- just know that interphase takes up most of time, only see chromosomes during cell division - Cycle regulated even with yeast- always stay same size- whi genes control when yeast will divide - Meiosis: generate sex cells- explains natural breeding (DNA from mother and father are slightly rearranged) o Cloning gets around this o Dangers  Every time you replicate DNA, telomeres get shorter  Cells die because you can’t replicate DNA anymore- theory of aging  Skin cells get 70-90 reps  *If population is genetically homogenous, and disease comes along, everyone will die- we need different alleles  * Think of this when we study agricultural biotechnology - Meiosis I- crossing over (telomeres mix up) - Meiosis II- independent assortment - Need genetic diversity for natural selection to work - Genetic programming- encode programs as chromosomes- evolve a solution to equation- approach used to get good answers for a lot of MP hard problems - Computer scientists taking advantage of biology - Trying to separate male and female sperm- could preselect gender of baby - 8,000,000 possible combinations of sperm in eggs- traditional breeding takes so long because of this- if we just put in genes for growth, time would be cut - Tetrad- two homologous chromosomes - Non-disjunction- abnormal- one cell gets one gamete and other gets three - Oogenesis- generating egg cells o Women are less busy- only one egg every now and then (other three cells become polar bodies) o Men: 250,000,000 sperm per day- full gametes - Egg and sperm: haploid - Somatic cells are body cells - Germ-line cells: egg/sperm- can also refer to stem cells o Genetic engineering in 1973- not allowed to manipulate germ-line- this would be passed on to subsequent generations- this is still law in most countries - *Somatic
More Less

Related notes for BIOL 1010

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.