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Elizabeth Nisbet (38)

Class Notes for Elizabeth Nisbet

Human Physiology

BIOL 2005 Lecture Notes - Vascular Endothelial Growth Factor, Mecha, Dendritic Cell

TUMOR IMMUNOLOGY Coley’s Toxin – activation of T cells to fight tumors MOUSE STUDIES: RAG2 knockout mice  no B/T cells  totally immunodeficint  MORE cancer RAG/STAT double knockouts are even more...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Interleukin 10, Interleukin 2, Central Tolerance

Outline of Lecture 13 T Cell Tolerance I. Overview A) Billingham neonatal graft experiments demonstrate learning of tolerance during development B) Shift of self-nonself ...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Leishmania, Natural Killer Cell, Gata3

IMMUNOLOGY T CELL EFFECTOR I: CD4 + T CELLS AND CYTOKINES -antigen recognition of MHC/Ag on APC does not occur at site of entry, but usually in lymph nodes/spleen -activated T cells then migrate to target ti...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Thymocyte, Apoptosis, Clonal Deletion

IMMUNOLOGY T CELL SELECTION AND CENTRAL TOLERANCE Tolerance-state of the immune system characterized by unresponsiveness to a particular antigen - ability to distinguish self from non self (unique...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Cytokine, Interleukin 2, Cd24

IMMUNOLOGY T CELL TOLERANCE -Generation of diversity is a stochastic post germ line encoded event. -The ability to discern btw harmful and innocuous antigens is learned in the neonatal period ...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Thymocyte, T-Cell Receptor, Clonal Deletion

T CELL TOLERANCE AND DEVELOPMENT TOLERANCE – unresponsiveness to a particular ag (usually self) self-tolerance is learned by developing immune system FREEMARTIN condition in twin catt...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Interleukin 10, Immunoglobulin A, Cytokine

T CELL TOLERANCE Immune activation vs. tolerance is CIRCUMSTANCE driven Janeway: immune system responds to antigen + presence of PAMP/PRR int. no PAMP/PRR interaction  tolerance Matz...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Antigen Processing, Hyper Igm Syndrome, Phos

IMMUNODEFICIENCY 150 known diseases 2 mechanisms of hypogammaglobulinemia  2 clinical manifestations 1) poor maturation of B cells: X-Linked Agammaglobulinemia prototypic antibody deficiency disease anti...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Exocytosis, Death Domain, Superoxide

IMMUNOLOGY CD8 CYTOLYTIC T LYMPHOCYTES (CTL) -CTLS lyse target cells that display processed foreign antigens bound to MHC molecules. -free virus and bacteria cant trigger CTLs -pathogens repli...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Rheumatoid Arthritis, Multiple Myeloma, Thymus

IMMUNE SYSTEM- protects host from diverse microorganisms and products -responds to anything perceived as foreign -attacking “self” = autoimmune disease Pathogens (small...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Interleukin 4, T Helper Cell, Glycolipid

NATURAL KILLER CELLS part of innate immunity; no prior exposure is necessary anti viral, anti-tumor, transplant rejection, materno-fetal interaction roles protection during T-cell priming period ...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Ctla-4, Chemokine, T Helper Cell

LYMPHOID ORGANS highly localized microenvironments are structural basis of immune response lymphocyte specificity is quite rare, as is their dispersement throughout the body soln: highly orchestrated movements of...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Lysosome, Antibody, Nadph Oxidase

INNATE IMMUNITY rapid (minutes/hours), generalized response to injury FEATURES: primary response shares effectors w/ adaptive immunity; stimulates adaptive immunity ...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Natural Killer Cell, Lipid Bilayer Fusion, Phase Response

IMMUNOLOGY EFFECTOR FUNCTIONS OF ANTIBODY -gene rearrangement and somatic mutation of variable region regionsdiverse Ab -rearrnged variable region can be associated w/different constant regi...

Biology
BIOL 2005
Elizabeth Nisbet
BIOL 2005 Lecture Notes - Macrophage, Polysaccharide, Heparin

EFFECTOR FUNCTIONS OF ANTIBODIES determined by constant regions of HC Ig’s in body fluids: IgG – internal IgA – external (on mucosal surfaces) IgM – first one made in reponse to antigen NO hyperm...

Biology
BIOL 2005
Elizabeth Nisbet
Permachart - Marketing Reference Guide: Extensor Carpi Ulnaris Muscle, Flexor Pollicis Longus Muscle, Abductor Digiti Minimi Muscle Of Hand

perm ach artsMT T rigger Points II: Extremities T rigger Points II: Extremities ...

ANAT - Anatomy
ANAT 14
All Professors
ANAT - Anatomy
ANAT 14
All Professors
ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Sacral Plexus, Lumbar Plexus, Sympathetic Ganglion

pe rm a ch ar ts MT Spinal Cord 2nd EDITION Figure ...

ANAT - Anatomy
ANAT 14
All Professors
Multicellular Biology - Reference Guides

This Guide is the progressive companion to the Cellular Biology title. The complexities of human physiology are made much clearer through the bright graphics and intelligently coordinated text boxes and glossaries that are...

ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Levator Veli Palatini, Orbicularis Oculi Muscle, Scalene Muscles

Muscular System: pe rm ac ha rts MT Head & Torso 2nd EDITION ...

ANAT - Anatomy
ANAT 14
All Professors
ANAT - Anatomy
ANAT 14
All Professors
ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Heart Valve, Inferior Vena Cava, Pulmonary Valve

permacharts TM Cardiovascular Physiology 2nd EDITION HEART STRUCTURE & FUNCTION ...

ANAT - Anatomy
ANAT 14
All Professors
ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Meiosis, Nuclear Membrane, Nuclear Pore

l e a r n • r e f e r e n c e • r e v i e w permacharts TM CCellular Biology BIOLOGY BASICS C...

ANAT - Anatomy
ANAT 14
All Professors
Cellular Respiration - Reference Guides

The specific aspects of cellular respiration are explained in this helpful Guide. The fundamental processes such as the electron transport chain, proton pumps, ATP synthetase, and glycolysis are each described with helpful...

ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Submandibular Duct, Parotid Duct, Palatine Tonsil

pe rm a ch a rtsMT DDigestive System 2nd EDITION Fi...

ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Antigen-Presenting Cell, Memory T Cell, Clonal Deletion

permacharts TM IImmunology 2nd EDITION G ENERAL INFORMATION - AN OVERVIEW ...

ANAT - Anatomy
ANAT 14
All Professors
Permachart - Marketing Reference Guide: Superior Frontal Sulcus, Inferior Parietal Lobule, Superior Frontal Gyrus

p erm ac hartsMT Brain 2nd EDITION FIGURE 1: GROSS ANATOMY (LATERAL VIEW) ...

ANAT - Anatomy
ANAT 173
All Professors
Permachart - Marketing Reference Guide: Superficial Palmar Arch, Costocervical Trunk, Thyrocervical Trunk

p erm a ch ar tsMT CCirculatory System 2nd EDITION Figure...

Biology
BI 361
All Professors

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