BIOL 2107 Lecture 2: Lecture 2
2 Nov 2020
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Document Summary
Benzer"s experimental approach to fine structure mapping of the rii locus. How mutagens alter dna: chemical action of mutagen. Replace a base: base analogs - chemical structure almost identical to normal base. Alter base structure and properties: hydroxylating agents add an oh group. Alter base structure and properties (cont): alkylating agents add ethyl or methyl groups. Pairing of complementary bases is the key to the transfer of information from dna to. Polarities of dna, rna, and polypeptides help guide the mechanisms of gene expression. Gene expression requires input of energy and participation of specific proteins and macromolecular assemblies. Mutations that change genetic information or obstruct the flow of its expression can have a dramatic effect on phenotype. Triplet codons of nucleotides represent individual amino acids: 61 codons represent the 20 amino acids. A gene"s nucleotide sequence is collinear with the amino acid sequence of the encoded polypeptide: Charles yanofsky - deduced key features of relationship between nucleotides and amino acids.
