BIOL 2201 Lecture Notes - Lecture 10: Paraoxonase, Clathrin, Endosome
8 Dec 2017
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Sn: endosome: ldl/receptor which is caused by the acidic environment. Contains hydrolytic enzymes which breaks down extracellular material and worn out organelles. Requires hydrogen pumps to maintain an acidic environment. Upr: increase in chaperone, er expansion, inhibition of protein syntheisis, opoptosis. Paraoxanase: an enzyme that has phosphorous base structure. By talking about the levels of biological organization. Peroxisome microsomes: are not naturally produced in the cell: liver, homogenize liver, centrifuge it (using gravity to separate organs) Cholesterol is for membrane fluidity and rigidity. Not all human paraoxonase have same functions. The slight different in the structure is due to genetics. The change in one base can change the amino acid and protein structure and causes different function. Depending on the polarity and different locations. If it does effect the protein or not. Opes are highly metabolized some of them depending on their structure. Polar bears are generally better metabolize the compounds, could be because the level of peroxisomes.
